The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemicals isopyrazam (CASRN 881685-58-1) and 3,3′,4,4′ tetrachloroazobenzene (CASRN 14047-09-7) as known to the State to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986. These actions are being proposed under the authoritative bodies listing mechanism.

The Office of Environmental Health Hazard Assessment (OEHHA) has proposed the adoption of a Proposition 65 Maximum Allowable Dose Level (MADL) of 660 micrograms per day for inhalation exposures to Chloroform (CASRN 67-66-3) by amending Section 25805(b). Chloroform is listed on Prop 65 as a chemical causing reproductive toxicity.

The Final Update on the Human Health Assessment of Long-Chain Chlorinated Alkanes has beeen released and published in the Canada Gazette, Part I.

In early 2012, the Environmental Protection Agency released two documents intended to describe the intial set of chemicals - or "Work Plan Chemicals" - that will be assessed and evaluated in regards to risk management. Although only seven chemicals were listed for review in 2012, a total of 83 chemicals have been targeted for future consideration.